Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethametryne SCHEMBL8827486 | 0.95 | HTT (0.42) | HTTPOLBGAACYP1A2CYP3A4 | |
| Dimethametryne SCHEMBL29391162 | 0.95 | HTT (0.42) | HTTPOLBGAACYP1A2CYP3A4 | |
| Dimethametryne SCHEMBL67453 | 0.95 | HTT (0.42) | HTTPOLBGAACYP1A2CYP3A4 | |
| Dimethametryne SCHEMBL30412502 | 0.95 | HTT (0.42) | HTTPOLBGAACYP1A2CYP3A4 | |
| Dimethametryne SCHEMBL5183719 | 0.95 | HTT (0.42) | HTTPOLBGAACYP1A2CYP3A4 | |
| Ametryne SCHEMBL65196 | 0.92 | POLB (0.54) | HTTPOLBGAACYP1A2CYP3A4 | |
| Ametryne SCHEMBL8541067 | 0.92 | POLB (0.54) | HTTPOLBGAACYP1A2CYP3A4 | |
| Ametryne SCHEMBL29368218 | 0.92 | POLB (0.54) | HTTPOLBGAACYP1A2CYP3A4 | |
| Prometryn SCHEMBL7945620 | 0.92 | POLB (0.54) | HTTPOLBGAACYP1A2CYP3A4 | |
| Prometryn SCHEMBL11160002 | 0.92 | POLB (0.54) | HTTPOLBGAACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245399-A1 | Pyrazole derivatives as herbicidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245399-A1 | Pyrazole derivatives as herbicidal compositions containing them | DDT, CBR3, CYP4X1 | HTT 3485/4885POLB 3720/4885GAA 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.