Ametryne

Ametryne

SCHEMBL65196

CCNc1nc(NC(C)C)nc(SC)n1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
GAA P10253 1/20 0.54
ALDH1A1 P00352 5/20 0.51
HTT P42858 4/20 0.51
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
MAPT P10636 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
TSHR P16473 1/20 0.49
CREBBP Q92793 1/20 0.49
LMNA P02545 1/20 0.47
MAPK1 P28482 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TP53 P04637 1/20 0.43
ALOX15 P16050 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prometryn SCHEMBL11160002 1.00 POLB (0.54) POLBGAAALDH1A1HTTCYP1A2
Prometryn SCHEMBL7945620 1.00 POLB (0.54) POLBGAAALDH1A1HTTCYP1A2
Ametryne SCHEMBL29368218 1.00 POLB (0.54) POLBGAAALDH1A1HTTCYP1A2
Ametryne SCHEMBL8541067 1.00 POLB (0.54) POLBGAAALDH1A1HTTCYP1A2
Ametryne SCHEMBL11801379 0.94 POLB (0.49) POLBGAAALDH1A1HTTCYP1A2
Ametryne SCHEMBL31093673 0.92 GAA (0.58) POLBGAAALDH1A1HTTCYP1A2
Prometryn SCHEMBL29456674 0.92 GAA (0.58) POLBGAAALDH1A1HTTCYP1A2
Ametryne SCHEMBL8812043 0.92 GAA (0.58) POLBGAAALDH1A1HTTCYP1A2
Prometryn SCHEMBL10969844 0.92 GAA (0.58) POLBGAAALDH1A1HTTCYP1A2
Dimethametryne SCHEMBL6364817 0.92 HTT (0.49) POLBGAAALDH1A1HTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20193 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102563-A1 DISUBSTITUTED PYRIMIDOPYRROLE ANALOG AND USE THEREOF 深圳湾实验室坪山生物医药研发转化中心 2026-05-21 WO claimed
CN-122056270-A Pesticide suspension concentrate and fertilizer composition thereof 诺力昂化学品国际有限公司 2026-05-19 CN claimed
CN-122004216-A Herbicide composition containing cyclohexene diketone lactic acid oxime ether derivative and application thereof 郑州手性药物研究院有限公司 2026-05-12 CN claimed
WO-2026088192-A1 METHOD FOR CONTROLLING WEED IN CEREAL CROPS ADAMA AGAN LTD. (IL) 2026-04-30 WO claimed
US-12605737-B2 Methods of temporarily enhancing the luster and brilliance of jewelry and gem stones ASHLEY PAUL (US) 2026-04-21 US claimed
US-20260096553-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2026-04-09 US claimed
EP-4713317-A1 A PROCESS FOR PURIFICATION OF ETHOFUMESATE Adama Agan Ltd. (IL) 2026-03-25 EP claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
CN-121577800-A Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) 2026-02-27 CN claimed
US-12550896-B2 Early applications of encapsulated acetamides for reduced injury in crops MONSANTO TECHNOLOGY LLC (US) 2026-02-17 US claimed
EP-0247721-A1 Alditol derivative esters of triclopyr , processes for their preparation and herbicidal compositions containing them THE DOW CHEMICAL COMPANY (US) 1987-12-02 EP claimed
US-4532732-A PLANT SAFENING AGENTS AND CHLOROACETANILIDE HERBICIDES FOR SERGHUM, RICE AND BARLEY CIBA-GEIGY CORPORATION (US) 1985-08-06 US claimed
US-4451279-A SAFENERS CIBA-GEIGY CORPORATION (US) 1984-05-29 US claimed
US-4449999-A PLANT SAFENING AGENTS; PROTECTIVE COATINGS FOR SEEDS CIBA-GEIGY CORPORATION (US) 1984-05-22 US claimed
EP-0107366-A1 Pyrrolidinone analogs and precursors ELI LILLY AND COMPANY (US) 1984-05-02 EP claimed
US-4394152-A Sulfur-containing oxime compounds for protecting cultivated plants CIBA-GEIGY CORPORATION (US) 1983-07-19 US claimed
US-4334910-A DIAMINOTHIOTRIAZINES AND SODIUM OR POTASSIUM BISULFATE RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1982-06-15 US claimed
EP-0009620-B1 HERBICIDES AND THEIR APPLICATION TO THE CONTROL OF WEEDS HOECHST AKTIENGESELLSCHAFT (DE) 1981-08-05 EP claimed
US-4012503-A TRIBUTYLTIN FLUORIDE, ZINC OXIDE, A CHLORO- OR THIO-DIAMINO-TRIAZINE; ANTIFOULANTS M & T CHEMICALS INC. (US) 1977-03-15 US claimed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US claimed