Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263251 | 0.79 | CPA1 (0.45) | MAPTSLC6A2SLC6A4CPA1ALDH1A1 | |
| SCHEMBL1306539 | 0.74 | MEN1 (0.42) | TP53MAPTSLC6A2SLC6A4CA2 | |
| SCHEMBL266009 | 0.69 | MEN1 (0.42) | CNR2MAPTCPA1CA2CA7 | |
| SCHEMBL3289735 | 0.67 | CPA1 (0.49) | TP53SLC6A2SLC6A4CPA1 | |
| SCHEMBL11036512 | 0.67 | CPA1 (0.49) | TP53SLC6A2SLC6A4CPA1 | |
| SCHEMBL187342 | 0.66 | CPA1 (0.52) | SLC6A2SLC6A4CPA1ALDH1A1 | |
| SCHEMBL10653829 | 0.65 | ACHE (0.43) | CNR2MAPTCNR1CA12CA9 | |
| SCHEMBL19326618 | 0.65 | CPA1 (0.47) | CYP2C19TP53CPA1ALDH1A1LMNA | |
| SCHEMBL7799742 | 0.65 | CPA1 (0.47) | TP53CPA1ALDH1A1 | |
| SCHEMBL28899283 | 0.65 | CYP2C19 (0.46) | CYP2C19CNR2MAPTCPA1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009800-B1 | 4-PHENYL-1,3-BENZODIAZEPINES, METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THE COMPOUNDS FOR USE AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-23 | — | — | EP | disclosed |