Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11162232 | 0.79 | CYP2C19 (0.42) | CPA1SLC6A2SLC6A4ALDH1A1MAPT | |
| SCHEMBL11036512 | 0.75 | CPA1 (0.49) | CPA1SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL3289735 | 0.75 | CPA1 (0.49) | CPA1SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL187342 | 0.74 | CPA1 (0.52) | CPA1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19326618 | 0.73 | CPA1 (0.47) | CPA1KMT2AALDH1A1 | |
| SCHEMBL27765113 | 0.73 | ADRA2B (0.53) | CPA1HPGDSLC6A2OPRK1SLC6A4 | |
| SCHEMBL5610245 | 0.72 | CPA1 (0.50) | CPA1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL28232642 | 0.72 | CPA1 (0.46) | CPA1SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9537072 | 0.71 | TSHR (0.46) | HPGDKMT2AALDH1A1MAPTPOLB | |
| SCHEMBL5609129 | 0.71 | CPA1 (0.49) | CPA1SLC6A2SLC6A4SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333930-A | TREATMENT OF CENTRAL NERVOUS DISORDERS, ANALGESICS, ANTIDEPRESSANTS | LABORATOIRES SARGET (FR) | 1982-06-08 | — | — | US | disclosed |