Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604828 | 0.85 | KMT2A (0.60) | CFTRL3MBTL1KMT2AOPRK1ALDH1A1 | |
| SCHEMBL3471111 | 0.84 | L3MBTL1 (0.55) | CFTRL3MBTL1KMT2AOPRK1 | |
| SCHEMBL11160397 | 0.83 | L3MBTL1 (0.57) | CFTRL3MBTL1KMT2AOPRK1ALDH1A1 | |
| SCHEMBL11167732 | 0.83 | MAPT (0.61) | L3MBTL1KMT2AOPRK1ALDH1A1MAPT | |
| SCHEMBL11861596 | 0.82 | L3MBTL1 (0.59) | CFTRL3MBTL1KMT2AOPRK1ALDH1A1 | |
| SCHEMBL11163429 | 0.82 | L3MBTL1 (0.53) | CFTRL3MBTL1KMT2AOPRK1ALDH1A1 | |
| SCHEMBL11469865 | 0.82 | L3MBTL1 (0.53) | CFTRL3MBTL1KMT2AOPRK1ALDH1A1 | |
| SCHEMBL11640838 | 0.81 | MAPT (0.58) | KMT2AALDH1A1MAPTMEN1HPGD | |
| SCHEMBL11165053 | 0.81 | L3MBTL1 (0.52) | CFTRL3MBTL1KMT2AOPRK1ALDH1A1 | |
| SCHEMBL11550177 | 0.81 | L3MBTL1 (0.52) | CFTRL3MBTL1KMT2AOPRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387223-A | Process for preparing 2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-07 | — | — | US | disclosed |
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |