Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604828 | 0.85 | KMT2A (0.60) | L3MBTL1KMT2AOPRK1MAPTMEN1 | |
| SCHEMBL11469865 | 0.84 | L3MBTL1 (0.53) | L3MBTL1KMT2AOPRK1MAPTMEN1 | |
| SCHEMBL3471111 | 0.84 | L3MBTL1 (0.55) | L3MBTL1KMT2AOPRK1CFTR | |
| SCHEMBL11160397 | 0.83 | L3MBTL1 (0.57) | L3MBTL1KMT2AOPRK1MAPTMEN1 | |
| SCHEMBL11167732 | 0.83 | MAPT (0.61) | L3MBTL1KMT2AOPRK1MAPTMEN1 | |
| SCHEMBL11864375 | 0.83 | MAPT (0.40) | L3MBTL1KMT2AMAPTMEN1LMNA | |
| SCHEMBL11868954 | 0.83 | CHEK1 (0.43) | L3MBTL1KMT2AMAPTMEN1LMNA | |
| SCHEMBL11462895 | 0.82 | MAPT (0.44) | MAPTLMNAPOLB | |
| SCHEMBL11861596 | 0.82 | L3MBTL1 (0.59) | L3MBTL1KMT2AOPRK1MAPTMEN1 | |
| SCHEMBL11163440 | 0.82 | CFTR (0.54) | L3MBTL1KMT2AOPRK1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | claimed |
| US-4387223-A | Process for preparing 2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-07 | — | — | US | disclosed |
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |