Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM6A | O15550 | 1/20 | 0.45 |
| ▸ | TET3 | O43151 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM4B | O94953 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767795 | 0.80 | KDM4E (0.64) | KDM4EEGLN1KDM6BKDM6ATET3 | |
| SCHEMBL11912045 | 0.78 | MEN1 (0.51) | KDM4EEGLN1KDM6BKDM6ATET3 | |
| SCHEMBL29462403 | 0.78 | KDM4E (0.73) | KDM4EEGLN1KDM6BKDM6ATET3 | |
| SCHEMBL163474 | 0.78 | KDM4E (0.73) | KDM4EEGLN1KDM6BKDM6ATET3 | |
| SCHEMBL27714474 | 0.77 | ELANE (0.44) | ELANEKDM4EEGLN1KDM6BKDM6A | |
| SCHEMBL13209656 | 0.77 | IMPDH2 (0.49) | KDM4EL3MBTL1GALR3ALDH1A1RAB9A | |
| SCHEMBL22889830 | 0.77 | KDM4E (0.54) | ELANEKDM4EEGLN1KDM6BKDM6A | |
| SCHEMBL3050409 | 0.76 | MEN1 (0.51) | KDM4EEGLN1KDM6BKDM6ATET3 | |
| Hydrochloric Acid SCHEMBL3310696 | 0.76 | KDM4E (0.71) | KDM4EEGLN1KDM6BKDM6ATET3 | |
| SCHEMBL4608765 | 0.76 | LMNA (0.49) | KDM4EEGLN1KDM6BKDM6ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4396620-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4382931-A | 3'-Substituted quinolinium cephalosporins | ELI LILLY AND COMPANY (US) | 1983-05-10 | — | — | US | disclosed |