SCHEMBL1116587

SCHEMBL1116587

CC(C)(C)OOC(C)(C)OC(=O)/C=C/C(=O)OC(C)(C)OOC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HCAR2 Q8TDS4 2/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1116591 0.92 HCAR2 (0.45) TSHRTDP1HCAR2KEAP1NFE2L2
SCHEMBL1116590 0.92 HCAR2 (0.45) TSHRTDP1HCAR2KEAP1NFE2L2
SCHEMBL4138048 0.82 TSHR (0.35) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL44412 0.77 TSHR (0.44) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL375029 0.76 HCAR2 (0.45) TDP1HCAR2KEAP1NFE2L2ALDH1A1
SCHEMBL43764 0.76 HCAR2 (0.45) TDP1HCAR2KEAP1NFE2L2ALDH1A1
SCHEMBL43004 0.76 HCAR2 (0.45) TDP1HCAR2KEAP1NFE2L2ALDH1A1
SCHEMBL44413 0.75 TSHR (0.42) TSHRTDP1ALDH1A1HSD17B10
SCHEMBL10595070 0.75 HCAR2 (0.46) HCAR2KEAP1NFE2L2
SCHEMBL3156753 0.75 HCAR2 (0.46) HCAR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2281778-B1 HYDROPHOBIC INORGANIC FINE PARTICLE AND TONER CANON KK (JP) 2016-08-31 EP disclosed
EP-1852747-B1 POSITIVELY CHARGEABLE DEVELOPER CANON KK (JP) 2014-01-22 EP disclosed
EP-2281778-A1 HYDROPHOBIC INORGANIC FINE PARTICLE AND TONER Canon Kabushiki Kaisha (JP) 2011-02-09 EP disclosed
US-7811734-B2 Hydrophobic inorganic fine particles and toner CANON KABUSHIKI KAISHA (JP) 2010-10-12 US disclosed
US-7740998-B2 Positively chargeable developer CANON KABUSHIKI KAISHA (JP) 2010-06-22 US disclosed
US-20100009277-A1 HYDROPHOBIC INORGANIC FINE PARTICLES AND TONER CANON KABUSHIKI KAISHA (JP) 2010-01-14 US disclosed
EP-1353236-B1 Toner CANON KK (JP) 2008-06-18 EP disclosed
EP-1852747-A1 POSITIVELY CHARGEABLE DEVELOPER Canon Kabushiki Kaisha (JP) 2007-11-07 EP disclosed
US-20060160006-A1 developer includes positively chargeable toner particles each containing a binder resin and magnetic iron oxide, silica and magnesium oxide as inorganic fine powder; capable of providing stable image quality without causing any image defect even in long-term use CANON KABUSHIKI KAISHA (JP) 2006-07-20 US disclosed
CN-1577123-A Magnetic toner CANON KK (JP) 2005-02-09 CN disclosed
US-6670087-B2 For use in electrophotography, electrostatic recording, magnetic recording and toner jet recording dielectric; dielectric dissipation factor CANON KABUSHIKI KAISHA (JP) 2003-12-30 US disclosed
US-20030198883-A1 Toner CANON KABUSHIKI KAISHA (JP) 2003-10-23 US disclosed
EP-1353236-A2 Toner CANON KABUSHIKI KAISHA (JP) 2003-10-15 EP disclosed
US-20020098431-A1 Toner, image-forming apparatus, process cartridge and image forming method CANON KABUSHIKI KAISHA (JP) 2002-07-25 US disclosed
EP-0725318-B1 Developer for developing an electrostatic image and image forming method CANON KK (JP) 1999-07-28 EP disclosed
US-5854365-A Toner for developing electrostatic image and method of manufacturing resin composition CANON KABUSHIKI KAISHA (JP) 1998-12-29 US disclosed
US-5700616-A Developer for developing an electrostatic image and image forming method CANON KABUSHIKI KAISHA (JP) 1997-12-23 US disclosed
EP-0725318-A1 Developer for developing an electrostatic image and image forming method CANON KABUSHIKI KAISHA (JP) 1996-08-07 EP disclosed
US-5489498-A RESIN COMPOSITION CONTAINING BINDER RESIN, LOW MOLECULAR WEIGHT WAX AND COLORING AGENT CANON KABUSHIKI KAISHA (JP) 1996-02-06 US disclosed