SCHEMBL1116591

SCHEMBL1116591

CC(C)(C)OOC(C)(C)OC(=O)C=CC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.45
TSHR P16473 4/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
TDP1 Q9NUW8 3/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
HSD17B10 Q99714 2/20 0.32
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
ALOX15 P16050 1/20 0.31
RECQL P46063 1/20 0.31
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1116590 1.00 HCAR2 (0.45) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1116587 0.92 TSHR (0.38) HCAR2TSHRTDP1ALDH1A1HSD17B10
Maleic Acid SCHEMBL2804945 0.82 TSHR (0.53) HCAR2TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL9380769 0.82 TSHR (0.53) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL642104 0.81 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL642105 0.81 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1964699 0.81 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL10595078 0.79 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL10595074 0.79 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL10596883 0.79 HCAR2 (0.54) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2281778-B1 HYDROPHOBIC INORGANIC FINE PARTICLE AND TONER CANON KK (JP) 2016-08-31 EP disclosed
EP-1852747-B1 POSITIVELY CHARGEABLE DEVELOPER CANON KK (JP) 2014-01-22 EP disclosed
EP-2281778-A1 HYDROPHOBIC INORGANIC FINE PARTICLE AND TONER Canon Kabushiki Kaisha (JP) 2011-02-09 EP disclosed
US-7811734-B2 Hydrophobic inorganic fine particles and toner CANON KABUSHIKI KAISHA (JP) 2010-10-12 US disclosed
US-7740998-B2 Positively chargeable developer CANON KABUSHIKI KAISHA (JP) 2010-06-22 US disclosed
US-20100009277-A1 HYDROPHOBIC INORGANIC FINE PARTICLES AND TONER CANON KABUSHIKI KAISHA (JP) 2010-01-14 US disclosed
EP-1353236-B1 Toner CANON KK (JP) 2008-06-18 EP disclosed
EP-1852747-A1 POSITIVELY CHARGEABLE DEVELOPER Canon Kabushiki Kaisha (JP) 2007-11-07 EP disclosed
US-20060160006-A1 developer includes positively chargeable toner particles each containing a binder resin and magnetic iron oxide, silica and magnesium oxide as inorganic fine powder; capable of providing stable image quality without causing any image defect even in long-term use CANON KABUSHIKI KAISHA (JP) 2006-07-20 US disclosed
CN-1577123-A Magnetic toner CANON KK (JP) 2005-02-09 CN disclosed
US-6670087-B2 For use in electrophotography, electrostatic recording, magnetic recording and toner jet recording dielectric; dielectric dissipation factor CANON KABUSHIKI KAISHA (JP) 2003-12-30 US disclosed
US-20030198883-A1 Toner CANON KABUSHIKI KAISHA (JP) 2003-10-23 US disclosed
EP-1353236-A2 Toner CANON KABUSHIKI KAISHA (JP) 2003-10-15 EP disclosed
US-20020098431-A1 Toner, image-forming apparatus, process cartridge and image forming method CANON KABUSHIKI KAISHA (JP) 2002-07-25 US disclosed
EP-0725318-B1 Developer for developing an electrostatic image and image forming method CANON KK (JP) 1999-07-28 EP disclosed
US-5854365-A Toner for developing electrostatic image and method of manufacturing resin composition CANON KABUSHIKI KAISHA (JP) 1998-12-29 US disclosed
US-5700616-A Developer for developing an electrostatic image and image forming method CANON KABUSHIKI KAISHA (JP) 1997-12-23 US disclosed
EP-0725318-A1 Developer for developing an electrostatic image and image forming method CANON KABUSHIKI KAISHA (JP) 1996-08-07 EP disclosed
US-5489498-A RESIN COMPOSITION CONTAINING BINDER RESIN, LOW MOLECULAR WEIGHT WAX AND COLORING AGENT CANON KABUSHIKI KAISHA (JP) 1996-02-06 US disclosed