SCHEMBL43764

SCHEMBL43764

CC(C)(C)OC(=O)C=CC(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.45
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45
DGAT1 O75907 1/20 0.40
ATM Q13315 1/20 0.33
PRKCA P17252 3/20 0.33
XPO1 O14980 1/20 0.33
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
USP2 O75604 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
NR1I2 O75469 1/20 0.32
PGR P06401 1/20 0.32
CYP3A4 P08684 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CYP2C9 P11712 1/20 0.32
SLC6A2 P23975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43004 1.00 HCAR2 (0.45) HCAR2KEAP1NFE2L2DGAT1ATM
SCHEMBL375029 1.00 HCAR2 (0.45) HCAR2KEAP1NFE2L2DGAT1ATM
SCHEMBL19008840 0.92 HCAR2 (0.39) HCAR2KEAP1NFE2L2DGAT1ATM
SCHEMBL642104 0.89 HCAR2 (0.54) HCAR2KEAP1NFE2L2DGAT1TDP1
SCHEMBL642105 0.89 HCAR2 (0.54) HCAR2KEAP1NFE2L2DGAT1TDP1
SCHEMBL3878185 0.89 HCAR2 (0.38) HCAR2KEAP1NFE2L2DGAT1PRKCA
SCHEMBL8451389 0.89 NFE2L2 (0.65) HCAR2KEAP1NFE2L2DGAT1LMNA
SCHEMBL14999614 0.89 HCAR2 (0.38) HCAR2KEAP1NFE2L2DGAT1PRKCA
SCHEMBL8449337 0.89 NFE2L2 (0.65) HCAR2KEAP1NFE2L2DGAT1LMNA
SCHEMBL8449347 0.89 NFE2L2 (0.65) HCAR2KEAP1NFE2L2DGAT1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036783-A Organosilicon modified polyaspartic acid ester polyurea and preparation method thereof 深圳市宝安区新材料研究院 2026-05-15 CN claimed
US-20260078213-A1 METHOD FOR PREPARING AN AMINOSUCCINIC RESIN WITH A LOW AMINE VALUE ARKEMA FRANCE (FR) 2026-03-19 US claimed
EP-4587497-A1 METHOD FOR PREPARING AN AMINOSUCCINIC RESIN WITH A LOW AMINE VALUE ARKEMA FRANCE (FR) 2025-07-23 EP claimed
CN-115244063-B Ligands for transition metal catalysts 罗特格斯新泽西州立大学 2025-03-07 CN claimed
WO-2024056688-A1 METHOD FOR PREPARING AN AMINOSUCCINIC RESIN WITH A LOW AMINE VALUE ARKEMA FRANCE (FR) 2024-03-21 WO claimed
CN-114805731-B Low-reactivity polyaspartic acid ester resin, preparation method, coating and preparation method 深圳飞扬骏研新材料股份有限公司 2023-10-20 CN claimed
CN-115181487-B High-molecular repairing agent for concrete ground tortoise cracks 星地元新材料股份有限公司 2023-07-25 CN claimed
CN-115181487-A Concrete floor tortoise crack polymer repairing agent 星地元新材料股份有限公司 2022-10-14 CN claimed
CN-115028832-A Preparation method of water-based polyaspartic ester resin and water-based PAE polyurea coating 浙江科技学院 2022-09-09 CN claimed
CN-114805731-A Low-reactivity polyaspartic acid ester resin, preparation method thereof, paint and preparation method thereof 深圳飞扬骏研新材料股份有限公司 2022-07-29 CN claimed
US-5525656-A HEAT SEALABLE COMPOSITION CONSISTING OF VINYL ESTER COPOLYMER IN ORGANIC SOLVENT; HALOGEN-FREE WACKER CHEMIE GMBH (DE) 1996-06-11 US claimed
EP-0244835-B1 LANGMUIR-BLODGETT ULTRATHIN MEMBRANE OF POLYFUMURATE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-08-26 EP claimed
EP-0192997-B1 METHOD FOR MODIFYING POLYFUMARIC ACID DIESTER NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-04-29 EP claimed
EP-0233299-B1 OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1991-03-13 EP claimed
US-4978722-A VAPOR PHASE POLYMERIZATION USING COORDINATION CATALYSTS AND CARBOXYLIC OR PHOSPHORUS ESTERS, AMINES OR AMIDES MITSUBISHI KASEI CORPORATION (JP) 1990-12-18 US claimed
US-4907038-A Langmuir Blodgett ultrathin membrane of polyfumarate NIPPON OIL AND FATS CO., LTD. (JP) 1990-03-06 US claimed
US-4855374-A Optical resin from diallyl esters NIPPON OIL AND FATS CO., LTD. (JP) 1989-08-08 US claimed
EP-0244835-A2 Langmuir-Blodgett ultrathin membrane of polyfumurate NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-11-11 EP claimed
EP-0233299-A1 Optical resin and process for preparing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-08-26 EP claimed
EP-0192997-A2 Method for modifying polyfumaric acid diester NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1986-09-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078213-A1 METHOD FOR PREPARING AN AMINOSUCCINIC RESIN WITH A LOW AMINE VALUE SRM, JMJD6, MAT1A HCAR2 165/4885KEAP1 936/4885NFE2L2 834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.