Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349165 | 0.83 | ALDH1A1 (0.33) | ALDH1A1LMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL10859951 | 0.82 | ALDH1A1 (0.33) | ALDH1A1LMNASMN1; SMN2HPGDKMT2A | |
| SCHEMBL11102955 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL11386517 | 0.79 | BCHE (0.32) | — | |
| SCHEMBL11387858 | 0.79 | CYP3A4 (0.43) | ALDH1A1LMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL11155957 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL11107974 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1LMNASMN1; SMN2HPGDMAPT | |
| Sulfuric Acid SCHEMBL11367780 | 0.77 | ALOX15 (0.35) | ALDH1A1LMNASMN1; SMN2HPGDKMT2A | |
| SCHEMBL11356953 | 0.77 | CYP3A4 (0.38) | ALDH1A1LMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL11310958 | 0.77 | IDO1 (0.33) | ALDH1A1LMNASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4372963-A | HISTAMINE ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-02-08 | — | — | US | disclosed |
| US-4285952-A | Pyridyl, thiazolyl and isothiazolyl alkyl bisamidines | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-08-25 | — | — | US | disclosed |
| US-4212875-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-07-15 | — | — | US | disclosed |