Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MC4R | P32245 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167965 | 0.98 | ALDH1A1 (0.54) | ALDH1A1HPGDMC4RUSP2TSHR | |
| SCHEMBL6069261 | 0.98 | ALDH1A1 (0.54) | ALDH1A1HPGDMC4RUSP2TSHR | |
| SCHEMBL6070037 | 0.98 | ALDH1A1 (0.54) | ALDH1A1HPGDMC4RUSP2TSHR | |
| SCHEMBL15171334 | 0.85 | HSD17B10 (0.46) | ALDH1A1HPGDMC4RUSP2TSHR | |
| Potassium Ion SCHEMBL11166150 | 0.84 | MC4R (0.54) | ALDH1A1HPGDMC4RUSP2TSHR | |
| SCHEMBL6070481 | 0.82 | TAAR1 (0.56) | ALDH1A1HPGDMC4RGAAL3MBTL1 | |
| SCHEMBL7763466 | 0.82 | TAAR1 (0.56) | ALDH1A1HPGDMC4RGAAL3MBTL1 | |
| SCHEMBL7763461 | 0.82 | TAAR1 (0.56) | ALDH1A1HPGDMC4RGAAL3MBTL1 | |
| SCHEMBL15937066 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDMC4RUSP2TSHR | |
| SCHEMBL11183404 | 0.80 | HPGD (0.47) | ALDH1A1HPGDMC4RUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387238-A | ANTIINFLAMMATORY, HYPOTENSIVE AGENTS, ENZYME INHIBITORS, ANTISPASMODIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-07 | — | — | US | disclosed |