Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070481 | 1.00 | TAAR1 (0.56) | TAAR1POLBGAANPSR1CA12 | |
| SCHEMBL7763461 | 1.00 | TAAR1 (0.56) | TAAR1POLBGAANPSR1CA12 | |
| SCHEMBL6070037 | 0.83 | ALDH1A1 (0.54) | GAANPSR1ALDH1A1MC4RMEN1 | |
| SCHEMBL11167965 | 0.83 | ALDH1A1 (0.54) | GAANPSR1ALDH1A1MC4RMEN1 | |
| SCHEMBL6069261 | 0.83 | ALDH1A1 (0.54) | GAANPSR1ALDH1A1MC4RMEN1 | |
| SCHEMBL11166155 | 0.82 | ALDH1A1 (0.53) | GAANPSR1ALDH1A1MC4RMEN1 | |
| SCHEMBL7762744 | 0.82 | CTSL (0.56) | TAAR1POLBGAAALDH1A1MC4R | |
| SCHEMBL7762722 | 0.81 | KMT2A (0.54) | KMT2AL3MBTL1MMP2 | |
| SCHEMBL7762733 | 0.81 | KMT2A (0.54) | KMT2AL3MBTL1MMP2 | |
| SCHEMBL8343183 | 0.81 | KMT2A (0.54) | KMT2AL3MBTL1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |