SCHEMBL11166167

SCHEMBL11166167

O=CNc1nc(C(=CI)C(=O)O)cs1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 3/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM1A O60341 4/20 0.33
AMY1A P0DUB6 3/20 0.33
POLB P06746 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11166163 1.00 L3MBTL1 (0.41) L3MBTL1GAASMN1; SMN2MAPTLMNA
SCHEMBL11162685 0.89 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2MAPTLMNA
SCHEMBL11162696 0.89 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2MAPTLMNA
SCHEMBL9477218 0.86 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2MAPTLMNA
SCHEMBL9477201 0.86 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2MAPTLMNA
SCHEMBL10610568 0.86 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2MAPTLMNA
Hydrochloric Acid SCHEMBL10920412 0.85 L3MBTL1 (0.39) L3MBTL1GAASMN1; SMN2MAPTLMNA
Ethane SCHEMBL10610246 0.84 L3MBTL1 (0.41) L3MBTL1GAASMN1; SMN2MAPTLMNA
SCHEMBL10606712 0.84 L3MBTL1 (0.38) L3MBTL1GAASMN1; SMN2MAPTLMNA
SCHEMBL10606708 0.84 L3MBTL1 (0.38) L3MBTL1GAASMN1; SMN2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0082498-A2 Beta-lactam compounds and process for the preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1983-06-29 EP disclosed