SCHEMBL9477201

SCHEMBL9477201

O=CNc1nc(/C(=C/Cl)C(=O)O)cs1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
GAA P10253 4/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM1A O60341 5/20 0.35
MAPT P10636 3/20 0.34
LMNA P02545 1/20 0.34
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AMY1A P0DUB6 3/20 0.33
POLB P06746 2/20 0.33
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9477218 1.00 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2KDM1AMAPT
SCHEMBL10610568 1.00 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2KDM1AMAPT
Hydrochloric Acid SCHEMBL10920412 0.98 L3MBTL1 (0.39) L3MBTL1GAASMN1; SMN2KDM1AMAPT
SCHEMBL10920407 0.88 GAA (0.38) L3MBTL1GAASMN1; SMN2KDM1AMAPT
SCHEMBL10920410 0.88 GAA (0.38) L3MBTL1GAASMN1; SMN2KDM1AMAPT
SCHEMBL11166163 0.86 L3MBTL1 (0.41) L3MBTL1GAASMN1; SMN2KDM1AMAPT
SCHEMBL11166167 0.86 L3MBTL1 (0.41) L3MBTL1GAASMN1; SMN2KDM1AMAPT
SCHEMBL11162685 0.85 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2KDM1AMAPT
SCHEMBL11162696 0.85 L3MBTL1 (0.40) L3MBTL1GAASMN1; SMN2KDM1AMAPT
SCHEMBL10606712 0.82 L3MBTL1 (0.38) L3MBTL1GAASMN1; SMN2KDM1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5242913-A Substituted 3-cephem compounds as antibacterial agents PFIZER INC. (US) 1993-09-07 US disclosed
WO-1993013108-A1 SUBSTITUTED 3-CEPHEM COMPOUNDS AS ANTIBACTERIAL AGENTS NAKANISHI SUSUMU (US) 1993-07-08 WO disclosed
US-5079242-A Substituted 3-cephem compounds as antibacterial agents PFIZER INC. (US) 1992-01-07 US disclosed