Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158661 | 0.85 | NPC1 (0.67) | ALDH1A1MAPTSMN1; SMN2GAAALOX12 | |
| SCHEMBL3050280 | 0.85 | RAB9A (0.71) | ALDH1A1MAPTSMN1; SMN2GAAALOX12 | |
| SCHEMBL5713568 | 0.85 | ALDH1A1 (0.78) | ALDH1A1MAPTSMN1; SMN2GAAALOX12 | |
| SCHEMBL11194030 | 0.85 | ALDH1A1 (0.65) | ALDH1A1MAPTSMN1; SMN2GAAALOX12 | |
| SCHEMBL3054870 | 0.85 | ALDH1A1 (0.72) | ALDH1A1MAPTSMN1; SMN2GAAALOX12 | |
| SCHEMBL11161487 | 0.84 | EPHX1 (0.74) | ALDH1A1MAPTEPHX1NPC1RAB9A | |
| SCHEMBL3047510 | 0.83 | EPHX1 (0.66) | ALDH1A1MAPTSMN1; SMN2ALOX12EPHX1 | |
| SCHEMBL18340971 | 0.83 | EPHX1 (0.65) | ALDH1A1MAPTSMN1; SMN2GAAALOX12 | |
| SCHEMBL16030259 | 0.82 | EPHX1 (0.64) | ALDH1A1MAPTSMN1; SMN2GAAALOX12 | |
| SCHEMBL16119683 | 0.81 | EPHX1 (0.81) | ALDH1A1MAPTSMN1; SMN2GAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017484-B1 | 2-IMIDAZOLINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0017484-A1 | 2-Imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-10-15 | — | — | EP | disclosed |