Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403688 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL5533990 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL5529970 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL10781761 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL9805552 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL11518064 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL9547388 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL10457059 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL10843670 | 0.80 | GAA (0.57) | ALDH1A1HPGDLMNAGAAALOX15 | |
| SCHEMBL6086755 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HPGDLMNAGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370332-A | MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-25 | — | — | US | disclosed |
| EP-0069373-A1 | (5R, 6R)-Penem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-01-12 | — | — | EP | disclosed |
| US-4292320-A | SMOOTH MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-09-29 | — | — | US | disclosed |
| US-3978063-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3963725-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-06-15 | — | — | US | disclosed |