Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403688 | 0.84 | ALDH1A1 (0.60) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL5529970 | 0.84 | ALDH1A1 (0.60) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL5533990 | 0.84 | ALDH1A1 (0.60) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL11166347 | 0.82 | ALDH1A1 (0.58) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL11518064 | 0.82 | ALDH1A1 (0.58) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL10672027 | 0.81 | GAA (0.59) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL10457059 | 0.81 | ALDH1A1 (0.56) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL6086755 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL9805552 | 0.79 | ALDH1A1 (0.55) | ALDH1A1POLBGAAALOX15HSD17B10 | |
| SCHEMBL14605923 | 0.79 | ALDH1A1 (0.55) | ALDH1A1POLBGAAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170876-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF RESTENOSIS COMPRISING ISOXAZOLE DERIVATIVES | SK HOLDINGS CO LTD (KR) | 2011-12-28 | — | — | EP | claimed |
| US-8518978-B2 | Pharmaceutical composition for prevention and treatment of restenosis comprising isoxazole derivatives | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2013-08-27 | — | — | US | disclosed |
| EP-2170876-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF RESTENOSIS COMPRISING ISOXAZOLE DERIVATIVES | SK HOLDINGS CO LTD (KR) | 2011-12-28 | — | — | EP | disclosed |
| US-7235575-B2 | Guanidine mimics as factor Xa inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2007-06-26 | — | — | US | disclosed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |
| US-4220644-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |