Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | PLK1 | P53350 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437314 | 1.00 | THRB (0.49) | THRBTHRAALDH1A1PLK1HPGD | |
| SCHEMBL11311491 | 1.00 | THRB (0.49) | THRBTHRAALDH1A1PLK1HPGD | |
| SCHEMBL10401962 | 1.00 | THRB (0.49) | THRBTHRAALDH1A1PLK1HPGD | |
| SCHEMBL11440269 | 1.00 | THRB (0.49) | THRBTHRAALDH1A1PLK1HPGD | |
| SCHEMBL6689838 | 1.00 | THRB (0.49) | THRBTHRAALDH1A1PLK1HPGD | |
| SCHEMBL3844526 | 1.00 | THRB (0.49) | THRBTHRAALDH1A1PLK1HPGD | |
| SCHEMBL11309662 | 1.00 | THRB (0.49) | THRBTHRAALDH1A1PLK1HPGD | |
| SCHEMBL11317920 | 1.00 | THRB (0.49) | THRBTHRAALDH1A1PLK1HPGD | |
| SCHEMBL3405047 | 0.93 | ALDH1A1 (0.50) | THRBTHRAALDH1A1HPGDMAPT | |
| SCHEMBL11437132 | 0.89 | TRPV1 (0.46) | THRBTHRAALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089154-A2 | Ethanolamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1983-09-21 | — | — | EP | disclosed |