Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.57 |
| ▸ | HTR2A | P28223 | 9/20 | 0.57 |
| ▸ | HTR2B | P41595 | 9/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.57 |
| ▸ | HTR3B | O95264 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5630950 | 0.83 | HTR2C (0.55) | HTR2CHTR2AHTR2BSLC6A4HTR3E | |
| SCHEMBL5365024 | 0.83 | ADRB1 (0.55) | HTR2CHTR2AHTR2BSLC6A4ADRB1 | |
| SCHEMBL17884647 | 0.83 | HTR2C (0.55) | HTR2CHTR2AHTR2BSLC6A4HTR3E | |
| SCHEMBL5315713 | 0.83 | HTR2C (0.56) | HTR2CHTR2AHTR2BSLC6A4HTR3E | |
| SCHEMBL23777584 | 0.83 | HTR2C (0.55) | HTR2CHTR2AHTR2BSLC6A4HTR3E | |
| Hydrochloric Acid SCHEMBL5373701 | 0.82 | ADRB1 (0.54) | HTR2CHTR2AHTR2BSLC6A4ADRB1 | |
| SCHEMBL988610 | 0.82 | SLC6A2 (0.57) | HTR2CHTR2AHTR2BSLC6A4HTR3E | |
| SCHEMBL4991540 | 0.81 | DRD2 (0.57) | HTR2CHTR2AHTR2BSLC6A4DRD2 | |
| SCHEMBL27523649 | 0.81 | HTR2A (0.53) | HTR2CHTR2AHTR2BSLC6A4HTR3E | |
| SCHEMBL27492442 | 0.81 | HTR2C (0.53) | HTR2CHTR2AHTR2BSLC6A4HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |