Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.86 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.72 |
| ▸ | CXCR6 | O00574 | 2/20 | 0.62 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11172665 | 1.00 | DRD3 (0.86) | DRD3OPRK1CXCR6CXCR4 | |
| SCHEMBL3364117 | 0.92 | DRD3 (1.00) | DRD3OPRK1CXCR6CXCR4 | |
| SCHEMBL11165630 | 0.92 | DRD3 (1.00) | DRD3OPRK1CXCR6CXCR4 | |
| SCHEMBL11204438 | 0.91 | DRD3 (0.72) | DRD3OPRK1CXCR6CXCR4 | |
| Tropapride SCHEMBL2110411 | 0.88 | DRD3 (0.79) | DRD3 | |
| SCHEMBL11297735 | 0.82 | DRD3 (0.70) | DRD3 | |
| SCHEMBL11166945 | 0.80 | DRD3 (0.78) | DRD3OPRK1CXCR6CXCR4 | |
| SCHEMBL8126666 | 0.78 | SIGMAR1 (0.67) | DRD3CXCR6 | |
| SCHEMBL8118831 | 0.78 | SIGMAR1 (0.75) | DRD3OPRK1CXCR6 | |
| SCHEMBL11167422 | 0.77 | DRD3 (0.74) | DRD3OPRK1CXCR6CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083737-A1 | N-azabicycloalkane benzamides, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-07-20 | — | — | EP | claimed |
| EP-0083737-A1 | N-azabicycloalkane benzamides, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-07-20 | — | — | EP | disclosed |