Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.74 |
| ▸ | CXCR6 | O00574 | 5/20 | 0.62 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364117 | 0.85 | DRD3 (1.00) | DRD3CXCR6CXCR4OPRK1DRD2 | |
| SCHEMBL11165630 | 0.85 | DRD3 (1.00) | DRD3CXCR6CXCR4OPRK1DRD2 | |
| SCHEMBL11166945 | 0.83 | DRD3 (0.78) | DRD3CXCR6CXCR4OPRK1DRD2 | |
| SCHEMBL11172665 | 0.77 | DRD3 (0.86) | DRD3CXCR6CXCR4OPRK1 | |
| SCHEMBL11166603 | 0.77 | DRD3 (0.86) | DRD3CXCR6CXCR4OPRK1 | |
| SCHEMBL10818632 | 0.76 | OPRK1 (0.71) | DRD3OPRK1 | |
| Tropapride SCHEMBL2110411 | 0.73 | DRD3 (0.79) | DRD3DRD2 | |
| SCHEMBL8119845 | 0.71 | SIGMAR1 (0.64) | DRD3DRD2 | |
| SCHEMBL8111456 | 0.71 | SIGMAR1 (0.80) | DRD3DRD2 | |
| SCHEMBL9412931 | 0.71 | DRD2 (0.69) | DRD3OPRK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083737-A1 | N-azabicycloalkane benzamides, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-07-20 | — | — | EP | claimed |
| EP-0083737-A1 | N-azabicycloalkane benzamides, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-07-20 | — | — | EP | disclosed |