Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602545 | 0.80 | HTR6 (0.56) | GLATSHRALDH1A1SMN1; SMN2HTR6 | |
| SCHEMBL12545615 | 0.79 | TTR (0.47) | ALDH1A1SMN1; SMN2HTR6POLBMAPT | |
| Hydrochloric Acid SCHEMBL30989178 | 0.79 | HTR6 (0.55) | GLATSHRALDH1A1SMN1; SMN2HTR6 | |
| SCHEMBL30832693 | 0.78 | GLA (0.44) | GLATSHRALDH1A1SMN1; SMN2HTR6 | |
| SCHEMBL11164601 | 0.76 | ALDH1A1 (0.44) | TSHRALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL9098638 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HTR6POLBMAPT | |
| SCHEMBL302695 | 0.74 | ALDH1A1 (0.53) | GLATSHRALDH1A1SMN1; SMN2HTR6 | |
| SCHEMBL11161006 | 0.74 | GAA (0.50) | GLATSHRALDH1A1MAPTLMNA | |
| SCHEMBL11159651 | 0.74 | MCL1 (0.48) | ALDH1A1POLBMAPTLMNAHTT | |
| SCHEMBL443530 | 0.73 | CA12 (0.55) | TSHRALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391816-A | ANTIDIABETIC AGENTS | AYERST, MCKENNA & HARRISON INC. (CA) | 1983-07-05 | — | — | US | disclosed |