Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176871 | 0.89 | TDP1 (0.56) | ALDH1A1TDP1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL4771360 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL25142579 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL4979237 | 0.82 | GABRA1 (0.49) | ALDH1A1TDP1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL377420 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1SMN1; SMN2HTTNR1H4 | |
| SCHEMBL30492996 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2MAPK1LMNAALOX15 | |
| SCHEMBL1851780 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2MAPK1LMNAALOX15 | |
| SCHEMBL13183891 | 0.81 | HTT (0.50) | ALDH1A1TDP1SMN1; SMN2HTTNR1H4 | |
| SCHEMBL21483747 | 0.81 | NPC1 (0.51) | SMN1; SMN2LMNANR1H4POLBMAPT | |
| SCHEMBL11164040 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TDP1SMN1; SMN2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034752-B1 | PHENOXYALKANE DERIVATIVE AND PROCESSES FOR PREPARING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1983-06-08 | — | — | EP | disclosed |
| EP-0034752-A1 | Phenoxyalkane derivative and processes for preparing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-09-02 | — | — | EP | disclosed |