Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | CETP | P11597 | 13/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745638 | 0.86 | NPC1 (0.66) | NPC1RAB9AMAPTTP53CETP | |
| SCHEMBL11446660 | 0.85 | NPC1 (0.64) | NPC1RAB9AMAPTTP53CETP | |
| SCHEMBL9681997 | 0.80 | NPC1 (0.71) | NPC1RAB9AMAPTTP53CETP | |
| SCHEMBL14666773 | 0.78 | NPC1 (0.57) | NPC1RAB9AMAPTTP53CETP | |
| SCHEMBL2997849 | 0.78 | SMN1; SMN2 (0.74) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL14266186 | 0.78 | MAPT (0.67) | NPC1RAB9AMAPTTP53CETP | |
| SCHEMBL19440714 | 0.78 | NPC1 (0.57) | NPC1RAB9AMAPTTP53CETP | |
| SCHEMBL11160763 | 0.77 | NPC1 (0.56) | NPC1RAB9AMAPTTP53CETP | |
| SCHEMBL11338188 | 0.76 | MAPT (0.51) | NPC1RAB9AMAPTTP53CETP | |
| SCHEMBL2249546 | 0.75 | NPC1 (0.64) | NPC1RAB9AMAPTTP53CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020298-B1 | BENZOXAZOLYL STILBENES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS FOR ORGANIC MATERIALS | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| US-4297234-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0020298-A1 | Benzoxazolyl stilbenes, process for their preparation and their use as optical brighteners for organic materials | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |