Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.74 |
| ▸ | RAB9A | P51151 | 11/20 | 0.74 |
| ▸ | HPGD | P15428 | 10/20 | 0.74 |
| ▸ | NPC1 | O15118 | 10/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.74 |
| ▸ | TP53 | P04637 | 8/20 | 0.74 |
| ▸ | CASP3 | P42574 | 4/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.62 |
| ▸ | RELA | Q04206 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947173 | 0.87 | ALDH1A1 (0.96) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL3288386 | 0.86 | ALDH1A1 (1.00) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL15047797 | 0.86 | ALDH1A1 (0.93) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL19380025 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL11642093 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL1736234 | 0.84 | KDM4E (0.68) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL10218249 | 0.83 | SMN1; SMN2 (0.82) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL17122218 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL10045311 | 0.81 | ALDH1A1 (0.84) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD | |
| SCHEMBL10061932 | 0.80 | SMN1; SMN2 (0.81) | SMN1; SMN2KDM4EALDH1A1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666902-A | Benzoxazole fluorescent whitening agent and preparation method thereof | 江苏格罗瑞化学有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-118666902-A | Benzoxazole fluorescent whitening agent and preparation method thereof | 江苏格罗瑞化学有限公司 | 2024-09-20 | — | — | CN | disclosed |
| US-10053428-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-08-21 | — | — | US | disclosed |
| US-20170260139-A1 | NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-14 | — | — | US | disclosed |
| US-20170260139-A1 | NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-14 | — | — | US | disclosed |
| US-20170260139-A1 | NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-14 | — | — | US | disclosed |
| US-9688636-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688636-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688636-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-27 | — | — | US | disclosed |
| EP-2875003-B1 | NEW 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS UND THEIR USE | Bayer Pharma AG (DE) | 2016-11-16 | — | — | EP | disclosed |
| US-20140031391-A1 | Novel 5-aminotetrahydroquinoline-2-carboxylic acids and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-01-30 | — | — | US | disclosed |
| CN-101177539-B | Hemicyanine dyes containing coumarin | Huaihai Technical College | 2010-10-27 | — | — | CN | disclosed |
| US-7781470-B2 | Aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-24 | — | — | US | disclosed |
| US-7674825-B2 | Dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20090203906-A1 | NOVEL AMINODICARBOXYLIC ACID DERIVATIVES HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2009-08-13 | — | — | US | disclosed |
| US-7517896-B2 | Aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2009-04-14 | — | — | US | disclosed |
| CN-101177539-A | Hemicyanine dyes containing coumarin | HUAIHAI TECHNICAL COLLEGE ZHAN (CN) | 2008-05-14 | — | — | CN | disclosed |
| US-20080058314-A1 | Novel dicarboxylic acid derivatives with pharmaceutical properties | BAYER AKTIENGESELLSCHAFT | 2008-03-06 | — | — | US | disclosed |
| US-7087644-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-08 | — | — | US | disclosed |
| US-20060094769-A1 | Novel aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031391-A1 | Novel 5-aminotetrahydroquinoline-2-carboxylic acids and their use | TNNT2, TNNI3, FABP3 | SMN1; SMN2 3433/4885KDM4E 3868/4885ALDH1A1 679/4885 |
| US-20090203906-A1 | NOVEL AMINODICARBOXYLIC ACID DERIVATIVES HAVING PHARMACEUTICAL PROPERTIES | DDC, AADAT, PTGIS | SMN1; SMN2 3924/4885KDM4E 244/4885ALDH1A1 214/4885 |
| US-10053428-B2 | 5-aminotetrahydroquinoline-2-carboxylic acids and their use | TNNT2, TNNI3, FABP3 | SMN1; SMN2 3139/4885KDM4E 3842/4885ALDH1A1 684/4885 |
| US-20080058314-A1 | Novel dicarboxylic acid derivatives with pharmaceutical properties | PC, GOT2, SDHA | SMN1; SMN2 3741/4885KDM4E 3141/4885ALDH1A1 302/4885 |
| US-20170260139-A1 | NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE | TNNT2, TNNI3, FABP3 | SMN1; SMN2 3433/4885KDM4E 3868/4885ALDH1A1 679/4885 |
| US-20060094769-A1 | Novel aminodicarboxylic acid derivatives having pharmaceutical properties | DDC, AADAT, PTGIS | SMN1; SMN2 3924/4885KDM4E 244/4885ALDH1A1 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.