Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167754 | 1.00 | NOD1 (0.59) | NOD1CXCL8PI4KBNOD2GAA | |
| SCHEMBL11156270 | 0.90 | NOD1 (0.57) | NOD1CXCL8PI4KBNOD2GAA | |
| SCHEMBL11148706 | 0.90 | NOD1 (0.57) | NOD1CXCL8PI4KBNOD2GAA | |
| SCHEMBL11156272 | 0.90 | NOD1 (0.57) | NOD1CXCL8PI4KBNOD2GAA | |
| SCHEMBL11148703 | 0.90 | NOD1 (0.57) | NOD1CXCL8PI4KBNOD2GAA | |
| SCHEMBL11160449 | 0.87 | NOD1 (0.54) | NOD1CXCL8PI4KBNOD2GAA | |
| SCHEMBL11160447 | 0.87 | NOD1 (0.54) | NOD1CXCL8PI4KBNOD2GAA | |
| Enviradene SCHEMBL10429408 | 0.85 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| Enviradene SCHEMBL10429409 | 0.85 | PI4KB (0.71) | PI4KBMAPK14CYP3A4 | |
| SCHEMBL11147024 | 0.85 | PI4KB (0.51) | NOD1CXCL8PI4KBNOD2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091794-A1 | Process for preparing 1.6-disubstituted 2-aminobenzimidazoles | ELI LILLY AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |