Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050164 | 0.80 | LOXL2 (0.61) | LOXL2CACNA1GCACNA1BCYP2A6SCN8A | |
| SCHEMBL23879203 | 0.79 | LOXL2 (0.71) | LOXL2CACNA1GCACNA1BCYP2A6SCN8A | |
| SCHEMBL5352838 | 0.77 | LOXL2 (0.53) | LOXL2CYP2A6CYP19A1CA12CA1 | |
| SCHEMBL5346390 | 0.77 | LOXL2 (0.53) | LOXL2CACNA1GCACNA1BCYP2A6SCN8A | |
| SCHEMBL19882179 | 0.77 | CA12 (0.49) | LOXL2CA12CA1CA2CA9 | |
| SCHEMBL6353289 | 0.76 | LOXL2 (0.61) | LOXL2CACNA1GCACNA1BCYP2A6SCN8A | |
| SCHEMBL1037055 | 0.76 | LOXL2 (0.67) | LOXL2CACNA1GCACNA1BCYP2A6SCN8A | |
| SCHEMBL2073087 | 0.76 | MEN1 (0.52) | CA12CA1CA2CA9MAOA | |
| SCHEMBL29912750 | 0.75 | LOXL2 (0.65) | LOXL2CACNA1GCACNA1BCYP2A6SCN8A | |
| SCHEMBL15826100 | 0.75 | DPP7 (0.58) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010369-B1 | CLAVULANIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-07-20 | — | — | EP | disclosed |
| US-4388300-A | OXAPENICILLIN ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-06-14 | — | — | US | disclosed |
| US-4343806-A | BACTERICIDES, LACTAMASE INHIBITORS | BEECHAM GROUP LIMITED (GB) | 1982-08-10 | — | — | US | disclosed |
| EP-0010369-A1 | Clavulanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-04-30 | — | — | EP | disclosed |