Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23879203 | 0.91 | LOXL2 (0.71) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL23145766 | 0.88 | LOXL2 (0.57) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL27596087 | 0.88 | LOXL2 (0.57) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL509459 | 0.88 | LOXL2 (0.57) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL25389992 | 0.88 | LOXL2 (0.57) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL15831741 | 0.88 | LOXL2 (0.62) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL2828109 | 0.85 | SCN8A (0.58) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL9885618 | 0.85 | SCN8A (0.55) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL9885619 | 0.85 | SCN8A (0.55) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL29038910 | 0.83 | SCN8A (0.54) | LOXL2CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943930-B | Synthesis process of Lasmidinan | 南京三元阳普医药科技有限公司 | 2022-11-01 | — | — | CN | disclosed |