Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197253 | 0.90 | SRC (0.42) | ALDH1A1SRCGAATSHRCYP1A2 | |
| SCHEMBL11267711 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SRCGAATSHRCYP1A2 | |
| SCHEMBL862366 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SRCGAATSHRCYP1A2 | |
| SCHEMBL13567140 | 0.78 | TDP1 (0.49) | ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL12001018 | 0.76 | ALDH1A1 (0.38) | ALDH1A1GAATSHRCYP1A2POLB | |
| SCHEMBL13812446 | 0.75 | ALDH1A1 (0.47) | ALDH1A1SRCGAATSHRCYP1A2 | |
| SCHEMBL15763 | 0.74 | CYP1A2 (0.43) | ALDH1A1SRCGAACYP1A2POLB | |
| SCHEMBL12740489 | 0.73 | CA12 (0.50) | ALDH1A1SRCGAACYP1A2POLB | |
| SCHEMBL14392306 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SRCGAATSHRCYP1A2 | |
| SCHEMBL13527615 | 0.72 | ALDH1A1 (0.44) | ALDH1A1SRCGAATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010440-B1 | PYROMELLITIC DIIMIDES, PROCESSES FOR THEIR PREPARATION, THESE COMPOUNDS IN ORALLY ADMINISTRABLE FORM FOR USE IN INCREASING THE FEED EFFICIENCY OF A RUMINANT ANIMAL AND COMPOSITIONS FOR THIS PURPOSE CONTAINING THEM | MERCK & CO. INC. (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4289784-A | ASYMMETRICALLY SUBSTITUTED | MERCK & CO., INC. (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0010440-A1 | Pyromellitic diimides, processes for their preparation, these compounds in orally administrable form for use in increasing the feed efficiency of a ruminant animal and compositions for this purpose containing them | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | disclosed |