Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | RORA | P35398 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | RORB | Q92753 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12659781 | 0.92 | TDP1 (0.45) | TDP1L3MBTL1ALDH1A1ADORA2BFAAH | |
| SCHEMBL10556725 | 0.89 | TDP1 (0.58) | TDP1L3MBTL1ALDH1A1ADORA2BFAAH | |
| SCHEMBL10554618 | 0.89 | TDP1 (0.58) | TDP1L3MBTL1ALDH1A1ADORA2BFAAH | |
| SCHEMBL18211042 | 0.88 | TDP1 (0.56) | TDP1L3MBTL1ALDH1A1ADORA2BFAAH | |
| SCHEMBL18211041 | 0.88 | TDP1 (0.56) | TDP1L3MBTL1ALDH1A1ADORA2BFAAH | |
| SCHEMBL25473109 | 0.84 | TDP1 (0.53) | TDP1L3MBTL1ALDH1A1ADORA2BFAAH | |
| SCHEMBL13744749 | 0.84 | TDP1 (0.53) | TDP1L3MBTL1ALDH1A1ADORA2BFAAH | |
| SCHEMBL12246385 | 0.84 | TDP1 (0.53) | TDP1L3MBTL1ALDH1A1ADORA2BFAAH | |
| SCHEMBL8777494 | 0.82 | TDP1 (0.68) | TDP1L3MBTL1ALDH1A1RORARORC | |
| SCHEMBL17798767 | 0.81 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9039946-B2 | Reversibly thermochromic compositions | BASF SE (DE) | 2015-05-26 | — | — | US | disclosed |
| US-9039946-B2 | Reversibly thermochromic compositions | BASF SE (DE) | 2015-05-26 | — | — | US | disclosed |
| US-20090302284-A1 | Reversibly Thermochromic Compositions | CIBA CORPORATION | 2009-12-10 | — | — | US | disclosed |
| US-20090302284-A1 | Reversibly Thermochromic Compositions | CIBA CORPORATION | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090302284-A1 | Reversibly Thermochromic Compositions | DHCR7, NES, DUT | TDP1 827/4885L3MBTL1 4265/4885ALDH1A1 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.