SCHEMBL11175136

SCHEMBL11175136

CCCCCCCCCCCCC(C)(SCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPK1 P28482 2/20 0.38
BLM P54132 2/20 0.38
ATM Q13315 2/20 0.38
HIF1A Q16665 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MAPT P10636 2/20 0.38
USP2 O75604 1/20 0.38
CYP2D6 P10635 1/20 0.38
LMNA P02545 3/20 0.37
RECQL P46063 1/20 0.37
F2R P25116 1/20 0.36
NR5A2 O00482 1/20 0.36
NR5A1 Q13285 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29171804 0.86 GAA (0.40) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL551941 0.85 GAA (0.39) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL11861605 0.84 PPARG (0.33) GAAKMT2A
SCHEMBL1873365 0.82 ALDH1A1 (0.41) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL11741056 0.82 HPN (0.49) GAAKMT2AMAPTLMNARECQL
SCHEMBL11742489 0.80 HPN (0.50) GAAKMT2AMAPTLMNARECQL
SCHEMBL9107152 0.80 EPHX2 (0.42) GAAKMT2AMEN1ALDH1A1CYP1A2
SCHEMBL10706899 0.77 ALDH1A1 (0.47) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL9431214 0.77 ALDH1A1 (0.47) GAAKMT2AMEN1ALDH1A1TSHR
SCHEMBL1403736 0.77 ALDH1A1 (0.47) GAAKMT2AMEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
EP-0018015-A1 Stabilized polyolefins filled with talc EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-10-29 EP disclosed
US-4208522-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4130710-A POLYOLEFIN STABILIZERS CIBA-GEIGY CORPORATION (US) 1978-12-19 US disclosed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed
US-4110305-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed
US-4070335-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed
US-4067848-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4051137-A Substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-4028334-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US disclosed
US-4007156-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-4007157-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-3992351-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1976-11-16 US disclosed
US-3969316-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-13 US disclosed
US-3968078-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-06 US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 US disclosed