Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.56 |
| ▸ | ALPL | P05186 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17069077 | 0.81 | BRD4 (0.64) | ALDH1A1GAADCUN1D1ALPLHSD17B10 | |
| SCHEMBL10476795 | 0.79 | NR1H2 (0.53) | ALDH1A1GAADCUN1D1ALPLNPC1 | |
| SCHEMBL6861707 | 0.78 | ALDH1A1 (0.57) | ALDH1A1GAADCUN1D1ALPLHSD17B10 | |
| SCHEMBL11174243 | 0.78 | NR1H2 (0.62) | ALDH1A1GAADCUN1D1ALPLNPC1 | |
| SCHEMBL17279795 | 0.78 | ALDH1A1 (0.60) | ALDH1A1GAADCUN1D1ALPLHSD17B10 | |
| SCHEMBL1528336 | 0.76 | ALDH1A1 (0.58) | ALDH1A1GAADCUN1D1ALPLHSD17B10 | |
| SCHEMBL10476791 | 0.76 | NR1H2 (0.73) | DCUN1D1ALPLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17280140 | 0.75 | NR1H2 (0.57) | ALDH1A1GAADCUN1D1ALPLHSD17B10 | |
| SCHEMBL11177912 | 0.75 | NR1H2 (0.64) | ALDH1A1DCUN1D1ALPLNPC1RAB9A | |
| SCHEMBL17280026 | 0.75 | DCUN1D1 (0.55) | ALDH1A1DCUN1D1ALPLNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379155-A | 3,5-Disubstituted-1H-1,2,4-triazole derivatives | GRUPPO LEPETIT S.P.A. (IT) | 1983-04-05 | — | — | US | disclosed |
| US-4370336-A | OXYTOCICS | GRUPPO LEPETIT S.P.A. (IT) | 1983-01-25 | — | — | US | disclosed |