Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861713 | 0.81 | NR1H2 (0.51) | ALDH1A1GAAMAPTRAB9ANPC1 | |
| SCHEMBL5681247 | 0.80 | TRPA1 (0.40) | ALDH1A1GAADCUN1D1ALPLHSD17B10 | |
| SCHEMBL11175366 | 0.78 | ALDH1A1 (0.57) | ALDH1A1GAADCUN1D1ALPLHSD17B10 | |
| SCHEMBL5678433 | 0.78 | NR1H2 (0.64) | DCUN1D1 | |
| SCHEMBL17279795 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAADCUN1D1ALPLHSD17B10 | |
| SCHEMBL11171303 | 0.77 | NR1H2 (0.60) | ALDH1A1ALPLMAPTRAB9ANPC1 | |
| SCHEMBL3500575 | 0.76 | NR1H2 (0.68) | DCUN1D1ALPLRAB9ANPC1 | |
| SCHEMBL29366389 | 0.76 | NR1H2 (0.68) | DCUN1D1ALPLRAB9ANPC1 | |
| SCHEMBL17280037 | 0.74 | NR1H2 (0.50) | ALDH1A1ALPLMAPTRAB9ANPC1 | |
| SCHEMBL25049797 | 0.73 | ALDH1A1 (0.67) | ALDH1A1GAADCUN1D1ALPLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797722-B2 | Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-09-28 | — | — | US | disclosed |