SCHEMBL11175367

SCHEMBL11175367

COC(=O)C(Cc1ccccc1)(Cc1ccccc1)C(=O)OC

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPRB P23467 14/20 0.69
PTPN1 P18031 4/20 0.69
PTPN2 P17706 2/20 0.69
PTPRA P18433 1/20 0.69
PTPRC P08575 1/20 0.53
PTPRG P23470 1/20 0.53
ACP1 P24666 1/20 0.53
KCNN4 O15554 1/20 0.52
ALDH1A1 P00352 1/20 0.49
RECQL P46063 1/20 0.49
MMP8 P22894 1/20 0.49
SRC P12931 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7975332 0.92 PTPN1 (0.64) PTPRBPTPN1PTPN2PTPRAPTPRC
SCHEMBL24872640 0.85 PTPRB (0.55) PTPRBPTPN1PTPN2PTPRAPTPRC
SCHEMBL11172488 0.85 PTPRB (0.58) PTPRBPTPN1PTPN2PTPRAPTPRC
SCHEMBL29256454 0.85 PTPRB (0.55) PTPRBPTPN1PTPN2PTPRAPTPRC
SCHEMBL707528 0.84 PTPN1 (0.56) PTPRBPTPN1PTPN2PTPRAPTPRC
SCHEMBL23752581 0.83 PTPRB (1.00) PTPRBPTPN1PTPN2PTPRAPTPRC
SCHEMBL293540 0.82 MMP8 (0.51) PTPRBPTPN1PTPN2PTPRAKCNN4
SCHEMBL4166692 0.82 PTPN1 (0.51) PTPRBPTPN1PTPN2PTPRAPTPRC
SCHEMBL21811199 0.82 MMP8 (0.51) PTPRBPTPN1PTPN2PTPRAKCNN4
SCHEMBL14518077 0.82 PTPN1 (0.51) PTPRBPTPN1PTPN2PTPRAPTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369275-A PHOTOSTABILITY FOR POLYMERS CIBA-GEIGY AG (CH) 1983-01-18 US disclosed
EP-0002260-B1 MALONIC ACID DERIVATIVES OF STERICALLY HINDERED PIPERIDINES, PROCESS FOR THEIR PREPARATION AND STABILISED ORGANIC MATTER CIBA-GEIGY AG (CH) 1982-07-14 EP disclosed
US-4293468-A Malonate derivatives as stabilizers for organic materials CIBA-GEIGY AG (CH) 1981-10-06 US disclosed
US-4256627-A COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4237297-A STERICALLY HINDERED PHOTOSTABILIZERS CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
EP-0002260-A2 Malonic acid derivatives of sterically hindered piperidines, process for their preparation and stabilised organic matter CIBA-GEIGY AG (CH) 1979-06-13 EP disclosed
EP-0001840-A2 Stabilising mixtures, process for stabilising synthetic materials against light with these mixtures and synthetic materials so stabilised CIBA-GEIGY AG (CH) 1979-05-16 EP disclosed