Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.56 |
| ▸ | PTPRB | P23467 | 12/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.53 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPRG | P23470 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975332 | 0.91 | PTPN1 (0.64) | PTPN1PTPRBPTPN2PTPRAPTPRC | |
| SCHEMBL11175367 | 0.84 | PTPRB (0.69) | PTPN1PTPRBPTPN2PTPRAPTPRC | |
| SCHEMBL395522 | 0.75 | SMN1; SMN2 (0.53) | PTPN1PTPRBPTPN2PTPRASMN1; SMN2 | |
| SCHEMBL7435532 | 0.74 | ALDH1A1 (0.59) | PTPN1PTPRBPTPN2PTPRAPTPRC | |
| SCHEMBL338742 | 0.74 | SMN1; SMN2 (0.61) | PTPN1PTPRBPTPN2PTPRASMN1; SMN2 | |
| SCHEMBL24872640 | 0.74 | PTPRB (0.55) | PTPN1PTPRBPTPN2PTPRAPTPRC | |
| SCHEMBL11172488 | 0.74 | PTPRB (0.58) | PTPN1PTPRBPTPN2PTPRAPTPRC | |
| SCHEMBL29256454 | 0.74 | PTPRB (0.55) | PTPN1PTPRBPTPN2PTPRAPTPRC | |
| SCHEMBL21269242 | 0.73 | SMN1; SMN2 (0.52) | PTPN1PTPRBPTPN2PTPRASMN1; SMN2 | |
| SCHEMBL21269412 | 0.73 | SMN1; SMN2 (0.52) | PTPN1PTPRBPTPN2PTPRASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8571659-B2 | Implantable medical device with chemical sensor and related methods | CARDIAC PACEMAKERS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120197231-A1 | IMPLANTABLE MEDICAL DEVICE WITH CHEMICAL SENSOR AND RELATED METHODS | CARDIAC PACEMAKERS, INC (US) | 2012-08-02 | — | — | US | disclosed |
| US-8126554-B2 | Implantable medical device with chemical sensor and related methods | CARDIAC PACEMAKERS, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-7809441-B2 | Implantable medical device with chemical sensor and related methods | CARDIAC PACEMAKERS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| EP-2024024-A1 | IMPLANTABLE MEDICAL DEVICE WITH CHEMICAL SENSOR AND RELATED METHODS | Cardiac Pacemakers, Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007137037-A1 | IMPLANTABLE MEDICAL DEVICE WITH CHEMICAL SENSOR AND RELATED METHODS | CARDIAC PACEMAKERS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-20070270674-A1 | Implantable Medical Device with Chemical Sensor and Related Methods | CARDIAC PACEMAKERS, INC. | 2007-11-22 | — | — | US | disclosed |
| US-20070270675-A1 | Implantable Medical Device with Chemical Sensor and Related Methods | CARDIAC PACEMAKERS, INC. | 2007-11-22 | — | — | US | disclosed |
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |