SCHEMBL11175437

SCHEMBL11175437

CCOc1ccc(P(=O)(Cl)Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.58
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 1/20 0.48
PLK1 P53350 1/20 0.47
PARP10 Q53GL7 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
LTA4H P09960 2/20 0.45
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 2/20 0.43
RAB9A P51151 1/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 1/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20879620 0.79 NQO1 (0.58) NQO1TDP1TSHRPLK1PARP10
SCHEMBL7213299 0.79 NQO1 (0.58) NQO1TDP1TSHRPLK1PARP10
1,4-Diethoxybenzene SCHEMBL28186701 0.76 NQO1 (1.00) NQO1TDP1TSHRPLK1PARP10
1,4-Diethoxybenzene SCHEMBL124015 0.76 NQO1 (1.00) NQO1TDP1TSHRPLK1PARP10
SCHEMBL2212578 0.76 CA1 (0.52) TDP1PLK1CA12CA1CA2
SCHEMBL9638869 0.75 NQO1 (0.52) NQO1TDP1TSHRPLK1PARP10
1,4-Diethoxybenzene SCHEMBL11794798 0.74 NQO1 (0.93) NQO1TDP1TSHRPLK1PARP10
SCHEMBL12353492 0.74 HPGD (0.36) TSHRCA2LMNA
SCHEMBL2470629 0.73 LTA4H (0.53) NQO1TDP1PLK1LTA4HALDH1A1
1,4-Diethoxybenzene SCHEMBL27616183 0.71 NQO1 (0.88) NQO1TDP1TSHRPLK1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4376064-A OXYGENATED COMPOUND OF PHOSPHORUS STANDARD OIL CO. (INDIANA) (US) 1983-03-08 US disclosed