Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11180123 | 0.90 | L3MBTL1 (0.54) | L3MBTL1LMNATDP1MAPTHPGD | |
| SCHEMBL11176476 | 0.87 | L3MBTL1 (0.46) | L3MBTL1LMNATDP1MAPTHPGD | |
| SCHEMBL11174792 | 0.83 | MAPT (0.44) | L3MBTL1LMNATDP1MAPTMEN1 | |
| SCHEMBL11167106 | 0.83 | L3MBTL1 (0.46) | L3MBTL1LMNATDP1MAPTHPGD | |
| SCHEMBL11177194 | 0.83 | L3MBTL1 (0.46) | L3MBTL1LMNATDP1MAPTHPGD | |
| SCHEMBL11344812 | 0.82 | L3MBTL1 (0.63) | L3MBTL1LMNATDP1MAPTHPGD | |
| SCHEMBL11152898 | 0.76 | SLC6A2 (0.39) | L3MBTL1LMNATDP1MAPTHPGD | |
| SCHEMBL18499131 | 0.72 | L3MBTL1 (0.55) | L3MBTL1LMNATDP1MAPTHPGD | |
| SCHEMBL11351610 | 0.71 | L3MBTL1 (0.45) | L3MBTL1LMNATDP1MAPTHPGD | |
| SCHEMBL14028414 | 0.70 | L3MBTL1 (0.62) | L3MBTL1LMNATDP1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007529-B1 | ANTIPROTOZOAL OXADIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-07-20 | — | — | EP | claimed |
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | claimed |
| EP-0007529-A1 | Antiprotozoal oxadiazole derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-02-06 | — | — | EP | claimed |
| EP-0007529-B1 | ANTIPROTOZOAL OXADIAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-07-20 | — | — | EP | disclosed |
| US-4294842-A | MALARIA | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| EP-0007529-A1 | Antiprotozoal oxadiazole derivatives, processes for their preparation and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |