Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11172769 | 0.92 | HTT (0.56) | GAAHTTNPSR1NPC1RAB9A | |
| SCHEMBL11181798 | 0.88 | KMT2A (0.61) | GAAHTTNPSR1NPC1RAB9A | |
| SCHEMBL5717689 | 0.85 | ITGB3 (0.63) | GAAHTTNPC1RAB9APOLB | |
| SCHEMBL4618907 | 0.84 | GAA (0.63) | GAAHTTNPC1RAB9APOLB | |
| SCHEMBL5717673 | 0.83 | GAA (0.56) | GAAHTTNPSR1NPC1RAB9A | |
| SCHEMBL10520532 | 0.83 | GAA (0.56) | GAAHTTNPSR1NPC1RAB9A | |
| SCHEMBL10130727 | 0.82 | GAA (0.69) | GAANPC1RAB9APOLBCYP1A2 | |
| SCHEMBL6245092 | 0.81 | GAA (1.00) | GAANPC1RAB9APOLBCYP1A2 | |
| SCHEMBL25681387 | 0.80 | GAA (0.61) | GAANPC1RAB9APOLBCYP1A2 | |
| SCHEMBL12426307 | 0.80 | GAA (0.82) | GAANPC1RAB9APOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405627-A | ANTISPASMODIC AGENTS; MUSCLE RELAXANTS; LOCAL ANESTHETICS | ITALIANA SCHOUM S.P.A. (IT) | 1983-09-20 | — | — | US | disclosed |