Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGAV | P06756 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175663 | 0.88 | GAA (0.67) | KMT2AHTTMEN1NPSR1CYP1A2 | |
| SCHEMBL11172769 | 0.83 | HTT (0.56) | KMT2AHTTMEN1NPSR1LMNA | |
| SCHEMBL27492954 | 0.80 | F2 (0.53) | KMT2AMEN1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL10946494 | 0.80 | MEN1 (0.80) | KMT2AHTTMEN1NPSR1LMNA | |
| SCHEMBL4575591 | 0.79 | KMT2A (0.68) | KMT2AHTTMEN1LMNAF2 | |
| SCHEMBL2899163 | 0.78 | NR3C1 (0.67) | KMT2ANPSR1F2NPC1RAB9A | |
| SCHEMBL1429119 | 0.78 | KMT2A (0.60) | KMT2AHTTMEN1NPSR1LMNA | |
| SCHEMBL10954626 | 0.77 | LMNA (0.86) | KMT2AHTTMEN1NPSR1LMNA | |
| SCHEMBL24254588 | 0.76 | F2 (0.60) | KMT2AHTTMEN1NPSR1LMNA | |
| SCHEMBL14826369 | 0.76 | LMNA (1.00) | KMT2AHTTMEN1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405627-A | ANTISPASMODIC AGENTS; MUSCLE RELAXANTS; LOCAL ANESTHETICS | ITALIANA SCHOUM S.P.A. (IT) | 1983-09-20 | — | — | US | disclosed |