Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MIF | P14174 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11168638 | 0.79 | MAPT (0.69) | KMT2AMEN1POLBALDH1A1MIF | |
| SCHEMBL11207676 | 0.78 | MAPT (0.58) | KMT2AMEN1POLBALDH1A1MIF | |
| SCHEMBL11168806 | 0.78 | KMT2A (0.55) | KMT2AMEN1POLBALDH1A1MIF | |
| SCHEMBL11164154 | 0.77 | MAPT (0.56) | KMT2AMEN1POLBALDH1A1MIF | |
| SCHEMBL11175929 | 0.76 | MAPT (0.56) | KMT2AMEN1POLBALDH1A1MIF | |
| SCHEMBL1011592 | 0.75 | POLB (0.68) | KMT2AMEN1POLBALDH1A1MIF | |
| SCHEMBL11163502 | 0.74 | MAPT (0.58) | KMT2AMEN1POLBALDH1A1MIF | |
| SCHEMBL11559468 | 0.74 | HPGD (0.46) | KMT2AMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL11163780 | 0.72 | MAPT (0.52) | KMT2AMEN1POLBALDH1A1MIF | |
| SCHEMBL5332558 | 0.72 | ALDH1A1 (0.64) | KMT2AMEN1POLBALDH1A1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094181-A1 | Use of thiadiazolylimidazolidinones to control aquatic vegetation | ELI LILLY AND COMPANY (US) | 1983-11-16 | — | — | EP | disclosed |
| EP-0093589-A1 | Thiadiazolylimidazolidinones, intermediates, formulations and herbicidal method | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |