Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175929 | 0.94 | MAPT (0.56) | MAPTRXFP1KMT2AMEN1POLB | |
| SCHEMBL11207676 | 0.89 | MAPT (0.58) | MAPTRXFP1KMT2AMEN1POLB | |
| SCHEMBL11164154 | 0.84 | MAPT (0.56) | MAPTRXFP1KMT2AMEN1POLB | |
| SCHEMBL11168638 | 0.84 | MAPT (0.69) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL11163780 | 0.83 | MAPT (0.52) | MAPTRXFP1KMT2AMEN1POLB | |
| SCHEMBL11560561 | 0.78 | MAPT (0.53) | MAPTRXFP1KMT2AMEN1POLB | |
| SCHEMBL11168806 | 0.76 | KMT2A (0.55) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL11175922 | 0.74 | KMT2A (0.60) | MAPTRXFP1KMT2AMEN1POLB | |
| SCHEMBL1011592 | 0.73 | POLB (0.68) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL5345562 | 0.73 | GLS (0.67) | MAPTRXFP1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094181-A1 | Use of thiadiazolylimidazolidinones to control aquatic vegetation | ELI LILLY AND COMPANY (US) | 1983-11-16 | — | — | EP | disclosed |
| EP-0093589-A1 | Thiadiazolylimidazolidinones, intermediates, formulations and herbicidal method | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |