Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 4/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 4/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 4/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328721 | 0.89 | PLAAT3 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL11642721 | 0.86 | PLAAT3 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL9404040 | 0.85 | F2RL1 (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL11221142 | 0.83 | L3MBTL1 (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL2547138 | 0.82 | PLAAT3 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL11178054 | 0.82 | FFAR1 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL11179937 | 0.82 | TDP1 (0.61) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL3839694 | 0.82 | IAPP (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL11174125 | 0.82 | FFAR1 (0.51) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL1295135 | 0.82 | TAAR1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4375474-A | BACTERICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1983-03-01 | — | — | US | disclosed |
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |