Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.75 |
| ▸ | CNR2 | P34972 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743079 | 0.86 | SMN1; SMN2 (1.00) | SMN1; SMN2CNR2TP53NPC1RAB9A | |
| SCHEMBL4719951 | 0.85 | SMN1; SMN2 (0.97) | SMN1; SMN2CNR2TP53NPC1RAB9A | |
| SCHEMBL4252422 | 0.82 | SMN1; SMN2 (0.77) | SMN1; SMN2CNR2TP53NPC1RAB9A | |
| SCHEMBL11184981 | 0.74 | MEN1 (0.43) | SMN1; SMN2TP53 | |
| SCHEMBL11888841 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2CNR2TP53NPC1RAB9A | |
| SCHEMBL29400012 | 0.73 | TDP1 (0.53) | SMN1; SMN2TP53NPC1RAB9AHTT | |
| SCHEMBL22499575 | 0.73 | TDP1 (0.53) | SMN1; SMN2TP53NPC1RAB9AHTT | |
| SCHEMBL11888955 | 0.73 | ALDH1A1 (0.58) | SMN1; SMN2RAB9AL3MBTL1POLBTDP1 | |
| SCHEMBL13532206 | 0.73 | TP53 (0.85) | SMN1; SMN2CNR2TP53NPC1RAB9A | |
| SCHEMBL31401017 | 0.72 | SMN1; SMN2 (0.70) | SMN1; SMN2CNR2TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4377521-A | ANTILIPEMIC | PFIZER INC. (US) | 1983-03-22 | — | — | US | disclosed |
| US-4138399-A | Sulfamylbenzoic acid | PFIZER INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4124590-A | CARDIOVASCULAR DISORDERS, ANTILIPEMIC AGENTS | PFIZER INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-3992441-A | ANTILIPEMIC | PFIZER INC. (US) | 1976-11-16 | — | — | US | disclosed |