SCHEMBL11176802

SCHEMBL11176802

CCCCCCCCCCCCCCCCCCCCN1C(C)(C)CC(OC)CC1(C)C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GUSB P08236 2/20 0.33
EBP Q15125 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
GBA2 Q9HCG7 11/20 0.32
GBA1 P04062 7/20 0.32
GAA P10253 2/20 0.32
UGCG Q16739 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11171968 1.00 GUSB (0.33) GUSBEBPSIGMAR1GNAI3GNAO1
SCHEMBL11170956 1.00 GUSB (0.33) GUSBEBPSIGMAR1GNAI3GNAO1
SCHEMBL11179109 0.91 MGLL (0.38)
SCHEMBL11179149 0.91 MGLL (0.38)
SCHEMBL11172869 0.85
SCHEMBL11170139 0.83 GBA1 (0.37) EBPSIGMAR1GBA2GBA1
SCHEMBL11177301 0.83 GBA1 (0.37) EBPSIGMAR1GBA2GBA1
SCHEMBL15966882 0.80 NAAA (0.37) GUSB
SCHEMBL7526280 0.80 NAAA (0.37) GUSB
SCHEMBL11243709 0.80 GUSB (0.30) GUSBEBPSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed