Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 4/20 | 0.36 |
| ▸ | ADH1C | P00326 | 3/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27808546 | 0.87 | FDPS (0.44) | FDPSALDH1A1ADH1AADH1CADH1B | |
| SCHEMBL28077115 | 0.83 | FDPS (0.48) | FDPSALDH1A1CES2CES1ADH1A | |
| SCHEMBL601669 | 0.79 | FDPS (0.45) | FDPSALDH1A1ADH1AADH1CADH1B | |
| SCHEMBL601670 | 0.79 | FDPS (0.45) | FDPSALDH1A1ADH1AADH1CADH1B | |
| SCHEMBL11174606 | 0.79 | ALDH1A1 (0.41) | FDPSALDH1A1ADH1AADH1CADH1B | |
| SCHEMBL1468324 | 0.79 | FDPS (0.45) | FDPSALDH1A1ADH1AADH1CADH1B | |
| SCHEMBL16149273 | 0.73 | FDPS (0.39) | FDPSADH1AADH1CADH1B | |
| SCHEMBL16149274 | 0.73 | FDPS (0.39) | FDPSADH1AADH1CADH1B | |
| SCHEMBL31634159 | 0.71 | FDPS (0.38) | FDPSALDH1A1ADH1AADH1CADH1B | |
| SCHEMBL754311 | 0.69 | PHGDH (0.46) | FDPSALDH1A1CES2CES1ADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421914-A | IMMUNE FUNCTION REGULATORS | TEIJIN LIMITED (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0049902-A2 | Novel thiazolo(3,2-a)pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1982-04-21 | — | — | EP | disclosed |