SCHEMBL11178014

SCHEMBL11178014

C=CCOc1c(Cl)c(OCC)c(S(=O)(=O)c2c(OCC)c(Cl)c(OCC=C)c(Cl)c2OCC)c(OCC)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5611697 0.70 HSD17B10 (0.35) MEN1KMT2ACA12CA1CA2
SCHEMBL9683876 0.70 HSD17B10 (0.37) MEN1KMT2ASMN1; SMN2MAPTLMNA
SCHEMBL11169010 0.67 SMN1; SMN2 (0.34) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL8224316 0.65 HTR2C (0.48) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL2239455 0.64 PTPRC (0.37) SMN1; SMN2NPC1RAB9APOLBMAPT
SCHEMBL12232724 0.63 NQO1 (0.36) LMNAALDH1A1MAPK1HTTCA1
SCHEMBL17058673 0.62 CA12 (0.63) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL10500362 0.61 CA12 (0.45) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL27958907 0.61 CA12 (0.45) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL7599115 0.61 CA12 (0.45) MEN1KMT2ASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369298-A Novel cured resin, process for production thereof, and lens composed of said resin from bis(alkyleneoxyphenyl)-diacrylate, bis(alkyleneoxyphenyl)diallyl ether, bis(alkyleneoxyphenyl)diallyl carbonate monomers TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1983-01-18 US disclosed