Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611697 | 0.90 | HSD17B10 (0.35) | HSD17B10GAATSHRTLR4HTR2C | |
| SCHEMBL11541914 | 0.72 | HSD17B10 (0.46) | HSD17B10GAATSHRHTR2CHTR2A | |
| SCHEMBL10648647 | 0.72 | KMT2A (0.47) | HSD17B10GAATSHRTLR4HTR2C | |
| SCHEMBL2239455 | 0.70 | PTPRC (0.37) | GAATSHRTLR4PTGS1PTGS2 | |
| SCHEMBL16395355 | 0.70 | HSD17B10 (0.39) | HSD17B10GAATSHRTLR4HTR2C | |
| SCHEMBL11583698 | 0.69 | CA1 (0.31) | CA1CA2CA9 | |
| SCHEMBL10642511 | 0.69 | HSD17B10 (0.44) | HSD17B10GAATSHRTLR4HTR2C | |
| SCHEMBL5954786 | 0.68 | TLR4 (0.34) | HSD17B10TLR4HTR2CHTR2AADRA2A | |
| SCHEMBL285173 | 0.68 | SMN1; SMN2 (0.36) | HSD17B10GAATSHRTLR4MEN1 | |
| SCHEMBL23215826 | 0.67 | LMNA (0.39) | HSD17B10GAATSHRHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106522-A | Liquid hydrophobic vehicle for electro-rheological fluid | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-04-21 | — | — | US | claimed |
| US-4049585-A | BUILDERS, LOW SUDSING | THE PROCTER & GAMBLE COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-3974092-A | COMPOUND, 6B, ORGANOALUMINUM COMPOUND, ETHER OF OLEFIN ALCOHOL | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |