SCHEMBL8224316

SCHEMBL8224316

C=CCOc1c(OCC)ccc(Cl)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 6/20 0.48
HTR2A P28223 4/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 5/20 0.41
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HTR2B P41595 2/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 1/20 0.39
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8219622 0.88 HTR2C (0.46) HTR2CHTR2AMEN1KMT2AADRA2A
SCHEMBL8227226 0.85 HTR2C (0.44) HTR2CHTR2AMEN1KMT2AADRA2A
SCHEMBL28627196 0.75 HTR2C (0.55) HTR2CHTR2AADRA2AADRA2BADRA2C
SCHEMBL23226950 0.75 HTR2C (0.55) HTR2CHTR2AMEN1KMT2AADRA2A
SCHEMBL28250971 0.75 CYP3A4 (0.42) HTR2CHTR2AMEN1KMT2AADRA2A
SCHEMBL8224319 0.74 ALDH1A1 (0.38) HTR2CHTR2ALMNAALDH1A1TSHR
SCHEMBL12300309 0.73 L3MBTL1 (0.42) HTR2CHTR2AALDH1A1TSHRL3MBTL1
SCHEMBL28286605 0.72 TSHR (0.44) HTR2CHTR2AMEN1KMT2AADRA2A
SCHEMBL26769631 0.72 LMNA (0.48) HTR2CHTR2AMEN1KMT2AADRA2A
SCHEMBL29745618 0.71 HTR2C (0.51) HTR2CHTR2AADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140274-A Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-31 US disclosed