Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263043 | 0.84 | ALDH1A1 (0.43) | MLYCDLMNANPSR1KDM4EALDH1A1 | |
| SCHEMBL11176149 | 0.75 | CNR1 (0.46) | PTGS2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11164503 | 0.75 | ALDH1A1 (0.39) | LMNANPSR1KDM4EALDH1A1TDP1 | |
| SCHEMBL10989518 | 0.72 | ALDH1A1 (0.47) | LMNANPSR1KDM4EALDH1A1TDP1 | |
| SCHEMBL5443200 | 0.72 | ALDH1A1 (0.47) | LMNANPSR1KDM4EALDH1A1TDP1 | |
| SCHEMBL7085313 | 0.70 | MAPK14 (0.59) | LMNANPSR1KDM4EALDH1A1TDP1 | |
| SCHEMBL27881874 | 0.69 | LMNA (0.59) | LMNANPSR1KDM4EALDH1A1TDP1 | |
| SCHEMBL11169683 | 0.69 | KMT2A (0.44) | LMNANPSR1KDM4EALDH1A1TDP1 | |
| SCHEMBL11165161 | 0.69 | NOX1 (0.53) | MLYCDLMNANPSR1KDM4EALDH1A1 | |
| SCHEMBL21852751 | 0.68 | ALDH1A1 (0.67) | LMNANPSR1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4372964-A | ANAGESIC, ANTIARTHRITIC | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-08 | — | — | US | disclosed |
| EP-0032113-A2 | Antiinflammatory 4,5-diaryl-alpha-(polyhaloalkyl)-1H-imidazole-2-methanols | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-07-15 | — | — | EP | disclosed |